Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10961483 | 0.84 | HPGD (0.38) | MAOAMAOBPOLLHPGDNISCH | |
| SCHEMBL7817693 | 0.80 | MAOA (0.50) | MAOAMAOBPOLLPARP1BRD4 | |
| SCHEMBL18181606 | 0.80 | MAOA (0.50) | MAOAMAOBPOLLPARP1BRD4 | |
| SCHEMBL10831325 | 0.77 | PARP1 (0.51) | MAOAMAOBPOLLPARP1BRD4 | |
| SCHEMBL10831092 | 0.74 | POLL (0.42) | MAOAMAOBPOLLPARP1KDM4E | |
| SCHEMBL10852030 | 0.71 | PARP1 (0.54) | MAOAMAOBPARP1BRD4CREBBP | |
| SCHEMBL10830897 | 0.68 | MAOA (0.49) | MAOAMAOBPOLLPARP1BRD4 | |
| SCHEMBL10966035 | 0.67 | ALDH1A1 (0.57) | ALDH1A1 | |
| SCHEMBL10955942 | 0.64 | POLL (0.41) | MAOAMAOBPOLLPARP1KDM4E | |
| SCHEMBL10955937 | 0.64 | POLL (0.41) | MAOAMAOBPOLLPARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4587259-A | Miticidal 2-(2-methyl-2,3-dihydro-benzofuran-7-yl)hydrazinecarboxylic acid esters | SHELL OIL COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| US-4550121-A | AGRICULTURE | SHELL OIL COMPANY (US) | 1985-10-29 | — | — | US | disclosed |