Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18181606 | 1.00 | MAOA (0.50) | MAOAMAOBPOLLBRD4CREBBP | |
| SCHEMBL10831325 | 0.84 | PARP1 (0.51) | MAOAMAOBPOLLBRD4CREBBP | |
| SCHEMBL11126847 | 0.80 | MAOA (0.42) | MAOAMAOBPOLLBRD4CREBBP | |
| SCHEMBL10831772 | 0.80 | MAOA (0.42) | MAOAMAOBPOLLBRD4CREBBP | |
| SCHEMBL10830897 | 0.77 | MAOA (0.49) | MAOAMAOBPOLLBRD4CREBBP | |
| SCHEMBL657712 | 0.72 | MAOA (0.45) | MAOAMAOBBRD4CREBBPPARP1 | |
| SCHEMBL9781320 | 0.71 | MAOA (0.38) | MAOAMAOBPOLLBRD4CREBBP | |
| SCHEMBL10831092 | 0.71 | POLL (0.42) | MAOAMAOBPOLLPARP1KDM4E | |
| SCHEMBL8458877 | 0.71 | MAOA (0.48) | MAOAMAOBPOLLBRD4CREBBP | |
| SCHEMBL13074639 | 0.71 | PARP1 (0.56) | MAOAMAOBPOLLBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287463-A1 | CONDENSED-RING PYRIMIDYLAMINO DERIVATIVE, PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND APPLICATIONS THEREOF | Guangzhou Maxinovel Pharmaceuticals Co., Ltd. (CN) | 2018-02-28 | — | — | EP | disclosed |
| US-20170362508-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20170362508-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-12-21 | — | — | US | disclosed |
| WO-2016169504-A1 | CONDENSED-RING PYRIMIDYLAMINO DERIVATIVE, PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND APPLICATIONS THEREOF | 广州再极医药科技有限公司 | 2016-10-27 | — | — | WO | disclosed |
| EP-0704067-B1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2001-08-01 | — | — | EP | disclosed |
| EP-0901485-A1 | 1,2-BENZOXATHIIN AND THIEPIN 2,2-DIOXIDE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997042185-A1 | 1,2-BENZOXATHIIN AND THIEPIN 2,2-DIOXIDE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
| EP-0704067-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0704067-A4 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES INC (US) | 1996-02-02 | — | — | EP | disclosed |
| US-5458815-A | Photochromic naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1995-10-17 | — | — | US | disclosed |
| US-5384077-A | Naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 1995-01-24 | — | — | US | disclosed |
| WO-1995000866-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1995-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362508-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | PBDC1, RCC1, PUF60 | MAOA 1396/4885MAOB 1669/4885POLL 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.