Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832426 | 0.79 | PADI4 (0.53) | ALDH1A1PADI4MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11602761 | 0.76 | PADI4 (0.44) | ALDH1A1PADI4MAPTMEN1KMT2A | |
| SCHEMBL9006276 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL579407 | 0.72 | RAB9A (0.40) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10832018 | 0.72 | RXFP1 (0.43) | ALDH1A1MAPTMAPK1RAB9AMEN1 | |
| SCHEMBL10719302 | 0.69 | RAB9A (0.67) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11418395 | 0.67 | ALDH1A1 (0.48) | ALDH1A1MAPK1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL14560577 | 0.66 | TDP1 (0.58) | ALDH1A1MAPTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL10832066 | 0.66 | PADI4 (0.44) | ALDH1A1PADI4MAPTMAPK1MEN1 | |
| SCHEMBL8264250 | 0.65 | MEN1 (0.66) | ALDH1A1MAPTMAPK1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578469-A | COUMARIN DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-25 | — | — | US | disclosed |