Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27074519 | 0.85 | FGFR1 (0.49) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL10832427 | 0.81 | KMT2A (0.50) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7706407 | 0.77 | MAPT (0.51) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL9006265 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL11481157 | 0.75 | MEN1 (0.52) | RXFP1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9006276 | 0.74 | ALDH1A1 (0.46) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL6275298 | 0.74 | HEXA (0.65) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL579407 | 0.74 | RAB9A (0.40) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL10832015 | 0.72 | ALDH1A1 (0.44) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL10719302 | 0.72 | RAB9A (0.67) | ALDH1A1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578469-A | COUMARIN DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-25 | — | — | US | disclosed |