Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833308 | 0.93 | ESR1 (0.53) | L3MBTL1ESR1ESR2KMT2AALDH1A1 | |
| SCHEMBL10832866 | 0.93 | L3MBTL1 (0.56) | L3MBTL1ESR1ESR2KMT2ACNR1 | |
| SCHEMBL10833631 | 0.88 | L3MBTL1 (0.64) | L3MBTL1ESR1ESR2KMT2ACNR1 | |
| SCHEMBL10832633 | 0.86 | L3MBTL1 (0.50) | L3MBTL1ESR1ESR2KMT2ACNR1 | |
| SCHEMBL10832774 | 0.79 | KMT2A (0.42) | KMT2ACNR1MEN1CNR2ALDH1A1 | |
| SCHEMBL3520738 | 0.78 | ESR1 (0.73) | L3MBTL1ESR1ESR2KMT2ACNR1 | |
| SCHEMBL11859297 | 0.78 | L3MBTL1 (0.58) | L3MBTL1ESR1ESR2PPARGPPARA | |
| SCHEMBL1966465 | 0.77 | L3MBTL1 (0.45) | L3MBTL1ESR1ESR2KMT2AMEN1 | |
| SCHEMBL2040594 | 0.77 | ESR1 (0.46) | L3MBTL1ESR1ESR2KMT2AALDH1A1 | |
| SCHEMBL10833316 | 0.76 | ALDH1A1 (0.49) | KMT2AMEN1HTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598085-A | Fungicidal 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-07-01 | — | — | US | disclosed |