Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | KLK7 | P49862 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832866 | 0.93 | L3MBTL1 (0.56) | L3MBTL1ESR1ESR2CNR1PPARG | |
| SCHEMBL10833631 | 0.88 | L3MBTL1 (0.64) | L3MBTL1ESR1ESR2CNR1PPARG | |
| SCHEMBL10832377 | 0.88 | ESR1 (0.48) | L3MBTL1ESR1ESR2TSHRPOLB | |
| SCHEMBL10832477 | 0.86 | L3MBTL1 (0.50) | L3MBTL1ESR1ESR2CNR1PPARG | |
| SCHEMBL9812912 | 0.86 | POLB (0.50) | NOS2ESR1ESR2KLK7TDP1 | |
| SCHEMBL3264863 | 0.85 | ESR1 (0.50) | NOS2ESR1ESR2TSHRMEN1 | |
| SCHEMBL10833308 | 0.79 | ESR1 (0.53) | L3MBTL1ESR1ESR2TDP1POLB | |
| SCHEMBL9896903 | 0.78 | ESR1 (0.73) | NOS2ESR1ESR2TSHRMEN1 | |
| SCHEMBL11861833 | 0.78 | ESR1 (0.47) | L3MBTL1NOS2ESR1ESR2TSHR | |
| SCHEMBL3520738 | 0.78 | ESR1 (0.73) | L3MBTL1NOS2ESR1ESR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598085-A | Fungicidal 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-07-01 | — | — | US | disclosed |