Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GPR6 | P46095 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832770 | 0.84 | HSD17B10 (0.52) | HSD17B10KDM4EGPR6SMN1; SMN2ALDH1A1 | |
| SCHEMBL11370675 | 0.84 | HPGD (0.58) | HSD17B10KMT2AMAPTKDM4EHPGD | |
| SCHEMBL11386026 | 0.82 | PKM (0.51) | KMT2AMAPTMEN1HPGDSMN1; SMN2 | |
| SCHEMBL11373554 | 0.81 | HPGD (0.60) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL10832384 | 0.81 | ALDH1A1 (0.56) | MAPTCYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL10833177 | 0.79 | ALDH1A1 (0.50) | HSD17B10KMT2AMAPTHPGDGPR6 | |
| SCHEMBL10832727 | 0.79 | MAPT (0.50) | KMT2AMAPTKDM4EGPR6SMN1; SMN2 | |
| SCHEMBL9037033 | 0.78 | ALDH1A1 (0.58) | KMT2AMAPTCYP1A2CYP2C19HPGD | |
| SCHEMBL11373667 | 0.78 | ALDH1A1 (0.54) | HSD17B10KMT2AMAPTMEN1CYP2C9 | |
| SCHEMBL7993058 | 0.77 | KMT2A (0.46) | HSD17B10KMT2AMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |
| EP-0083729-A1 | Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1983-07-20 | — | — | EP | disclosed |
| US-4269990-A | CHEMICAL INTERMEDIATES FOR 1-UNSUBSTITUTED-2-(4-INDANYL- OR 5-NAPHTHYLAMINO)-2-IMIDAZOLINE, USEFUL AS DRUGS | BASF AKTIENGESELLSCHAFT (DE) | 1981-05-26 | — | — | US | disclosed |