Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GPR6 | P46095 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832689 | 0.84 | HSD17B10 (0.63) | HSD17B10TSHRKDM4EALDH1A1GAA | |
| SCHEMBL10832408 | 0.82 | POLB (0.54) | TDP1ALDH1A1GAAPOLB | |
| SCHEMBL10832384 | 0.78 | ALDH1A1 (0.56) | TSHRALDH1A1GAASMN1; SMN2POLB | |
| SCHEMBL16026516 | 0.74 | ALDH1A1 (0.61) | TSHRTDP1KDM4EALDH1A1GAA | |
| SCHEMBL10832289 | 0.74 | GPR6 (0.43) | HSD17B10TSHRTDP1KDM4EALDH1A1 | |
| SCHEMBL10832293 | 0.74 | GPR6 (0.43) | HSD17B10TSHRTDP1KDM4EALDH1A1 | |
| SCHEMBL3390530 | 0.73 | MAPT (0.55) | HSD17B10TSHRKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9621122 | 0.73 | ALDH1A1 (0.60) | TSHRTDP1KDM4EALDH1A1GAA | |
| SCHEMBL11386026 | 0.72 | PKM (0.51) | ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL11370675 | 0.72 | HPGD (0.58) | HSD17B10KDM4EALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |
| EP-0083729-A1 | Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1983-07-20 | — | — | EP | disclosed |