Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | GRK5 | P34947 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PRKX | P51817 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14790520 | 0.81 | MAPK14 (0.47) | MAPK14ADORA2A | |
| SCHEMBL23559176 | 0.78 | MAPK14 (0.42) | MAPK14ADORA2AALDH1A1LMNATP53 | |
| SCHEMBL11752620 | 0.75 | MAPK14 (0.49) | MAPK14ADORA2A | |
| SCHEMBL10832326 | 0.74 | PTGS2 (0.46) | MAPK14ADORA2AMAPTALDH1A1LMNA | |
| SCHEMBL10832926 | 0.73 | MAPK14 (0.45) | MAPK14ADORA2AADORA1CHEK1ABL1 | |
| SCHEMBL11753280 | 0.68 | MAPK14 (0.45) | MAPK14ADORA2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8060009 | 0.67 | PTGS1 (0.47) | MAPK14ADORA2AALDH1A1LMNATP53 | |
| SCHEMBL24212672 | 0.67 | MAPK14 (0.49) | MAPK14ADORA2ALMNATP53HTT | |
| SCHEMBL11750960 | 0.66 | MAPK14 (0.43) | MAPK14ADORA2AADORA1ALDH1A1CYP1A2 | |
| SCHEMBL926216 | 0.65 | MAPK14 (0.55) | MAPK14ADORA2AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596816-A | Pharmaceuticals | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| EP-0092239-A2 | Oxazole derivatives, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-10-26 | — | — | EP | disclosed |