Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833670 | 0.80 | HSD11B1 (0.42) | HSD11B1L3MBTL1NPC1MAPTC1R | |
| SCHEMBL5548035 | 0.77 | MBNL1 (0.47) | L3MBTL1NPC1MAPTC1RNOTUM | |
| SCHEMBL10834073 | 0.75 | AKR1C3 (0.48) | HSD11B1L3MBTL1C1RNOTUMPSMB8 | |
| SCHEMBL10834069 | 0.74 | FFAR1 (0.45) | C1RTDP1ALDH1A1 | |
| SCHEMBL5541542 | 0.74 | MAPT (0.49) | HSD11B1L3MBTL1NPC1MAPTTSHR | |
| SCHEMBL24910269 | 0.72 | HSD11B1 (0.43) | HSD11B1L3MBTL1C1RNOTUMPSMB8 | |
| SCHEMBL10832531 | 0.72 | GPBAR1 (0.38) | NPC1MAPTC1RPTPN1ALDH1A1 | |
| SCHEMBL6344165 | 0.71 | PIK3R1 (0.50) | HSD11B1L3MBTL1NPC1MAPTC1R | |
| SCHEMBL28302854 | 0.70 | DPP4 (0.45) | HSD11B1C1RNOTUMPSMB8DPP4 | |
| SCHEMBL15495466 | 0.70 | PDK2 (0.53) | HSD11B1L3MBTL1NPC1MAPTNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596816-A | Pharmaceuticals | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| EP-0092239-A2 | Oxazole derivatives, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-10-26 | — | — | EP | disclosed |