SCHEMBL6344165

SCHEMBL6344165

FC(F)(F)c1ccccc1-c1nc2ccccc2nc1-c1ccccc1C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3R1 P27986 2/20 0.50
PIK3CA P42336 2/20 0.50
C1R P00736 1/20 0.49
ALDH1A1 P00352 2/20 0.48
NPC1 O15118 1/20 0.48
MAPT P10636 1/20 0.48
AHR P35869 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP1A2 P05177 4/20 0.47
CYP2D6 P10635 3/20 0.47
CLK4 Q9HAZ1 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2C9 P11712 1/20 0.47
RECQL P46063 1/20 0.47
HSD11B1 P28845 1/20 0.47
ACP1 P24666 1/20 0.46
BACE1 P56817 1/20 0.45
NOTUM Q6P988 1/20 0.44
DPP4 P27487 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12111498 0.86 PIK3R1 (0.64) PIK3R1PIK3CAALDH1A1CYP1A2CYP2D6
SCHEMBL12111574 0.81 PIK3R1 (0.59) PIK3R1PIK3CAALDH1A1NPC1MAPT
SCHEMBL12111561 0.81 PIK3R1 (0.59) PIK3R1PIK3CAALDH1A1NPC1MAPT
SCHEMBL12111663 0.81 PIK3R1 (0.59) PIK3R1PIK3CAALDH1A1NPC1MAPT
SCHEMBL12111634 0.81 PIK3R1 (0.59) PIK3R1PIK3CAALDH1A1NPC1MAPT
SCHEMBL12595510 0.78 PIK3R1 (0.56) PIK3R1PIK3CAALDH1A1MAPTRAB9A
SCHEMBL197671 0.77 HSD11B1 (0.56) ALDH1A1CYP1A2CYP2D6CYP2C19HSD11B1
SCHEMBL2489961 0.77 MAPT (0.73) ALDH1A1NPC1MAPTAHRRAB9A
SCHEMBL18034158 0.76 TRPA1 (0.48) PIK3R1PIK3CAC1RNPC1RAB9A
SCHEMBL18131657 0.76 CYP1A2 (0.49) C1RALDH1A1MAPTCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050191527-A1 Organometallic compound containing quinoxaline structure and light emitting element SANYO ELECTRIC CO., LTD. (JP) 2005-09-01 US disclosed