Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 4/20 | 0.36 |
| ▸ | PHOSPHO1 | Q8TCT1 | 4/20 | 0.36 |
| ▸ | PMM2 | O15305 | 3/20 | 0.36 |
| ▸ | MPI | P34949 | 3/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373396 | 0.75 | MPI (0.57) | G6PDPHOSPHO1PMM2MPIMIF | |
| SCHEMBL10833396 | 0.69 | CASP3 (0.59) | G6PDPHOSPHO1PMM2MPICASP3 | |
| SCHEMBL31568860 | 0.65 | MAPK1 (0.53) | MAPK1MCL1OGG1MEN1ALDH1A1 | |
| SCHEMBL2970289 | 0.63 | MAPT (0.48) | ERCC5FEN1MAPK1MCL1OGG1 | |
| SCHEMBL8371739 | 0.62 | MPI (0.62) | G6PDPHOSPHO1PMM2MPICASP3 | |
| SCHEMBL151907 | 0.60 | KDM4E (0.54) | MAPK1MCL1OGG1MEN1ALDH1A1 | |
| SCHEMBL9310672 | 0.60 | CYP1A2 (0.48) | FEN1MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL3150930 | 0.60 | LMNA (0.41) | MAPK1MCL1OGG1MEN1ALDH1A1 | |
| SCHEMBL2472914 | 0.59 | KDM4E (0.57) | MAPK1MCL1OGG1MEN1ALDH1A1 | |
| SCHEMBL7226057 | 0.57 | GPR3 (0.54) | MAPK1MCL1OGG1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599427-A | FUNGICIDES BACTERICIDES SLIMICIDES ALGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-08 | — | — | US | disclosed |
| EP-0106243-B1 | AZOLYL-METHYL AMINES, THEIR PREPARATION AND THEIR USE IN MICROBICIDE COMPOSITIONS | BAYER AG (DE) | 1986-05-28 | — | — | EP | disclosed |
| EP-0106243-A1 | Azolyl-methyl amines, their preparation and their use in microbicide compositions | BAYER AG (DE) | 1984-04-25 | — | — | EP | disclosed |