Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | SLC47A2 | Q86VL8 | 2/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.32 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831790 | 0.88 | ACHE (0.34) | SLC22A2CA12SLC22A3CA1CA2 | |
| SCHEMBL10832537 | 0.79 | SMN1; SMN2 (0.40) | LMNAPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL10833240 | 0.77 | — | — | |
| SCHEMBL10832725 | 0.77 | CYP3A4 (0.39) | HRH2ACHE | |
| SCHEMBL10832107 | 0.75 | CYP3A4 (0.38) | HRH2ACHE | |
| SCHEMBL10832985 | 0.73 | MAPT (0.36) | HRH2ACHE | |
| SCHEMBL10832464 | 0.72 | HRH2 (0.40) | SLC22A2CA12SLC22A3CA1CA2 | |
| SCHEMBL10832074 | 0.70 | ACHE (0.33) | SLC22A2CA12SLC22A3CA1CA2 | |
| SCHEMBL10833045 | 0.66 | SMN1; SMN2 (0.42) | LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL11229688 | 0.66 | HRH2 (0.37) | SLC22A2CA12SLC22A3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578478-A | Thiazole derivatives and procedure of synthesis thereof | KOTOBUKI SEIYAKU COMPANY LIMITED (JP) | 1986-03-25 | — | — | US | disclosed |