Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832537 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL10831790 | 0.78 | ACHE (0.34) | MAPTLMNA | |
| SCHEMBL4886906 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL10832464 | 0.72 | HRH2 (0.40) | KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5988033 | 0.70 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL855213 | 0.70 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL4890454 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL1118859 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL10833142 | 0.66 | SLC22A2 (0.32) | KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL14825340 | 0.66 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578478-A | Thiazole derivatives and procedure of synthesis thereof | KOTOBUKI SEIYAKU COMPANY LIMITED (JP) | 1986-03-25 | — | — | US | disclosed |