Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 3/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | SLC47A2 | Q86VL8 | 2/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833142 | 0.88 | SLC22A2 (0.32) | ACHEHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL10832464 | 0.83 | HRH2 (0.40) | ACHEHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL10833045 | 0.78 | SMN1; SMN2 (0.42) | LMNAMAPT | |
| SCHEMBL10832074 | 0.77 | ACHE (0.33) | ACHEHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL10832695 | 0.77 | CYP3A4 (0.41) | ACHEHRH2CYP3A4CYP2D6MAPT | |
| SCHEMBL10833240 | 0.70 | — | — | |
| SCHEMBL10958735 | 0.69 | MEN1 (0.42) | ACHEHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL4348396 | 0.67 | ACHE (0.52) | ACHEHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL11229688 | 0.67 | HRH2 (0.37) | ACHEHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL10961352 | 0.67 | HRH2 (0.38) | ACHEHRH2SLC22A2CA12SLC22A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578478-A | Thiazole derivatives and procedure of synthesis thereof | KOTOBUKI SEIYAKU COMPANY LIMITED (JP) | 1986-03-25 | — | — | US | disclosed |