Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831833 | 0.93 | CRHBP (0.41) | GPR183CRHBPCRHR2GPR6 | |
| SCHEMBL10831783 | 0.87 | SCN5A (0.39) | CRHBPCRHR2 | |
| SCHEMBL10831824 | 0.83 | GPR6 (0.43) | CRHBPCRHR2GPR6 | |
| SCHEMBL10831616 | 0.82 | HSD11B1 (0.39) | HSD11B1MGLLGPR6DRD2 | |
| SCHEMBL11363350 | 0.81 | HPGD (0.43) | GPR183HSD11B1CRHBPCRHR2GPR6 | |
| SCHEMBL11363360 | 0.81 | HPGD (0.43) | GPR183HSD11B1CRHBPCRHR2GPR6 | |
| SCHEMBL10832582 | 0.80 | GPR6 (0.42) | HSP90AA1HSD11B1MGLLGPR6 | |
| SCHEMBL11371555 | 0.80 | GPR183 (0.39) | GPR183MGLLCRHBPCRHR2GPR6 | |
| SCHEMBL11375171 | 0.79 | POLB (0.40) | CRHBPCRHR2GPR6 | |
| SCHEMBL11375172 | 0.79 | POLB (0.40) | CRHBPCRHR2GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |