Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833605 | 0.80 | CA12 (0.40) | TAAR1ALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL10833316 | 0.77 | ALDH1A1 (0.49) | TAAR1ALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL10833135 | 0.77 | KDM4E (0.50) | TAAR1ALDH1A1SMN1; SMN2KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL10833061 | 0.75 | CYP19A1 (0.38) | TAAR1KDM4ESIGMAR1IGF1RATM | |
| SCHEMBL10833320 | 0.75 | TAAR1 (0.42) | TAAR1KMT2A | |
| SCHEMBL24603011 | 0.74 | IGF1R (0.52) | TAAR1ALDH1A1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9802284 | 0.73 | L3MBTL1 (0.51) | TAAR1SMN1; SMN2KMT2AMEN1ATM | |
| SCHEMBL28049956 | 0.73 | TAAR1 (0.51) | TAAR1MTNR1AMTNR1BSIGMAR1AOC3 | |
| SCHEMBL7452354 | 0.71 | ALDH1A1 (0.56) | TAAR1ALDH1A1GAA | |
| SCHEMBL7535470 | 0.71 | TAAR1 (0.56) | TAAR1HPGDMTNR1AMTNR1BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598085-A | Fungicidal 1-(2-aryl-2-R-ethyl)-1H-1,2,4-triazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-07-01 | — | — | US | disclosed |