SCHEMBL28049956

SCHEMBL28049956

COc1ccccc1CCC(O)C(O)CO

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.51
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
AGTR1 P30556 1/20 0.46
AOC3 Q16853 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
KCNH2 Q12809 1/20 0.45
MPO P05164 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
IDO1 P14902 1/20 0.43
ABCB1 P08183 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535470 0.81 TAAR1 (0.56) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL3952965 0.78 IDO1 (0.49) TAAR1AGTR1LMNACYP1A2IDO1
SCHEMBL31147801 0.77 TAAR1 (0.60) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL7636733 0.77 TAAR1 (0.60) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL29474956 0.76 TAAR1 (0.64) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL852646 0.76 TAAR1 (0.64) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL23987637 0.75 MTNR1A (0.56) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL28858018 0.75 TAAR1 (0.75) TAAR1MTNR1AMTNR1BSIGMAR1AOC3
SCHEMBL6172464 0.75 ABCB1 (0.49) TAAR1SIGMAR1LMNAKCNH2ABCB1
SCHEMBL11555598 0.74 TAAR1 (0.49) TAAR1MTNR1AMTNR1BSIGMAR1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294410-A Pair of phenyl unsaturated triol isomer compounds separated and purified from chloranthus angustifolius, and preparation method and application thereof UNIV HUNAN AGRICULTURAL 2016-02-03 CN disclosed