Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477732 | 0.92 | KMT2A (0.70) | KMT2AHSD17B10MAPTGAASMN1; SMN2 | |
| SCHEMBL30874080 | 0.92 | KMT2A (0.70) | KMT2AHSD17B10MAPTGAASMN1; SMN2 | |
| Benzoic Acid SCHEMBL23122871 | 0.87 | KMT2A (0.64) | KMT2AHSD17B10MAPTGAASMN1; SMN2 | |
| SCHEMBL1043660 | 0.87 | ALOX5 (0.63) | KMT2AHSD17B10MAPTGAASMN1; SMN2 | |
| Phenol SCHEMBL28288930 | 0.86 | KMT2A (0.67) | KMT2AHSD17B10MAPTGAASMN1; SMN2 | |
| SCHEMBL30848573 | 0.84 | KMT2A (0.59) | KMT2AHSD17B10MAPTGAASMN1; SMN2 | |
| SCHEMBL7535342 | 0.84 | KMT2A (0.59) | KMT2AHSD17B10MAPTGAASMN1; SMN2 | |
| SCHEMBL29613809 | 0.83 | ALOX5 (0.71) | KMT2AHSD17B10MAPTGAASMN1; SMN2 | |
| SCHEMBL5081762 | 0.83 | ALOX5 (0.71) | KMT2AHSD17B10MAPTGAASMN1; SMN2 | |
| SCHEMBL28679045 | 0.83 | KMT2A (0.67) | KMT2AHSD17B10MAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613620-A | MICROBIOCIDES | ELI LILLY AND COMPANY (US) | 1986-09-23 | — | — | US | disclosed |