Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833567 | 0.88 | CA12 (0.61) | KCNH2CA12CA1CA2CA7 | |
| SCHEMBL12314517 | 0.88 | GRM5 (0.58) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL10834508 | 0.87 | LTA4H (0.58) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL28345910 | 0.80 | CA12 (0.64) | GRM5KCNH2CA12CA1CA2 | |
| Diphenylether SCHEMBL10632533 | 0.78 | LTA4H (0.57) | KCNH2CA12CA1CA2CA7 | |
| SCHEMBL10834444 | 0.78 | CA12 (0.51) | GRM5CA12CA1CA2CA7 | |
| SCHEMBL7510158 | 0.77 | KCNH2 (0.57) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL9999906 | 0.76 | TEAD4 (0.56) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL14394344 | 0.76 | TEAD4 (0.56) | GRM5KCNH2CA12CA1CA2 | |
| SCHEMBL425356 | 0.76 | HTT (0.69) | CA1CA2LTA4HMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4607035-A | MITICIDES | MONTEDISON S.P.A. (IT) | 1986-08-19 | — | — | US | claimed |
| US-4607035-A | MITICIDES | MONTEDISON S.P.A. (IT) | 1986-08-19 | — | — | US | disclosed |