Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 12/20 | 0.56 |
| ▸ | EDNRB | P24530 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834781 | 1.00 | EDNRA (0.56) | EDNRAEDNRBMEN1CYP2C9TSHR | |
| SCHEMBL10834904 | 0.81 | AMY1A (0.61) | MEN1TSHRKMT2A | |
| SCHEMBL10834896 | 0.81 | AMY1A (0.61) | MEN1TSHRKMT2A | |
| SCHEMBL10834280 | 0.77 | BRD4 (0.74) | MEN1CYP2C9TSHRKMT2A | |
| SCHEMBL10835311 | 0.77 | BRD4 (0.74) | MEN1CYP2C9TSHRKMT2A | |
| SCHEMBL10834754 | 0.72 | HSD11B1 (0.48) | MEN1CYP2C9TSHRKMT2A | |
| SCHEMBL10834749 | 0.72 | HSD11B1 (0.48) | MEN1CYP2C9TSHRKMT2A | |
| SCHEMBL10834633 | 0.71 | AMY1A (0.60) | MEN1TSHRKMT2A | |
| SCHEMBL10834640 | 0.71 | AMY1A (0.60) | MEN1TSHRKMT2A | |
| SCHEMBL7716850 | 0.70 | EDNRA (1.00) | EDNRAEDNRBMEN1CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4628083-A | ANTIFERTILITY ENZYME INHIBITOR, PROSTAGLANDIN INFLUENCE | PHARMACIA AB (SE) | 1986-12-09 | — | — | US | disclosed |
| EP-0021229-B1 | ARYLAZO COMPOUNDS, THEIR PREPARATION AND THEIR USE | PHARMACIA AB (SE) | 1982-12-22 | — | — | EP | disclosed |
| EP-0021229-A1 | Arylazo compounds, their preparation and their use | PHARMACIA AB (SE) | 1981-01-07 | — | — | EP | disclosed |