Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834896 | 1.00 | AMY1A (0.61) | AMY1AKDRTSHRLMNAGAA | |
| SCHEMBL10834633 | 0.90 | AMY1A (0.60) | AMY1AKDRTSHRLMNAGAA | |
| SCHEMBL10834640 | 0.90 | AMY1A (0.60) | AMY1AKDRTSHRLMNAGAA | |
| Salazosulfadimidine SCHEMBL150333 | 0.84 | AMY1A (0.63) | AMY1AKDRTSHRLMNAGAA | |
| Salazosulfadimidine SCHEMBL31424085 | 0.84 | AMY1A (0.63) | AMY1AKDRTSHRLMNAGAA | |
| SCHEMBL10834769 | 0.81 | EDNRA (0.56) | TSHRMEN1KMT2A | |
| SCHEMBL10834781 | 0.81 | EDNRA (0.56) | TSHRMEN1KMT2A | |
| SCHEMBL10834280 | 0.79 | BRD4 (0.74) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10835311 | 0.79 | BRD4 (0.74) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL17011237 | 0.76 | GAA (0.64) | AMY1AKDRTSHRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4628083-A | ANTIFERTILITY ENZYME INHIBITOR, PROSTAGLANDIN INFLUENCE | PHARMACIA AB (SE) | 1986-12-09 | — | — | US | disclosed |
| EP-0021229-B1 | ARYLAZO COMPOUNDS, THEIR PREPARATION AND THEIR USE | PHARMACIA AB (SE) | 1982-12-22 | — | — | EP | disclosed |
| EP-0021229-A1 | Arylazo compounds, their preparation and their use | PHARMACIA AB (SE) | 1981-01-07 | — | — | EP | disclosed |