Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 17/20 | 0.61 |
| ▸ | RARB | P10826 | 17/20 | 0.61 |
| ▸ | RARG | P13631 | 16/20 | 0.61 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL10834874 | 0.94 | RARA (0.56) | RARARARBRARGRXRACYP1A2 | |
| SCHEMBL8900020 | 0.84 | RARB (0.65) | RARARARBRARGRXRACYP1A2 | |
| SCHEMBL9359619 | 0.84 | RARB (0.63) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL10834419 | 0.81 | RARA (0.64) | RARARARBRARGRXRACYP1A2 | |
| SCHEMBL1615553 | 0.81 | RXRA (0.46) | RARARARBRARGRXRACYP1A2 | |
| SCHEMBL29606831 | 0.81 | RXRA (0.46) | RARARARBRARGRXRACYP1A2 | |
| SCHEMBL26151172 | 0.80 | RARB (0.54) | RARARARBRARGRXRA | |
| Methane SCHEMBL10834484 | 0.80 | RARA (0.62) | RARARARBRARGRXRACYP1A2 | |
| SCHEMBL10834477 | 0.78 | RARB (0.59) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL10834705 | 0.78 | RARB (0.59) | RARARARBRARGRXRACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581380-A | TREATMENT OF SKIN DISORDERS;ANTIINFLAMMATORY AGENTS | Groupement Economique dite: Centre National de Recherches Dermatologiques C.I.R.D. (FR) | 1986-04-08 | — | — | US | claimed |
| US-4581380-A | TREATMENT OF SKIN DISORDERS;ANTIINFLAMMATORY AGENTS | Groupement Economique dite: Centre National de Recherches Dermatologiques C.I.R.D. (FR) | 1986-04-08 | — | — | US | disclosed |