Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.70 |
| ▸ | HTR2A | P28223 | 5/20 | 0.70 |
| ▸ | HTR1A | P08908 | 4/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375348 | 0.84 | DRD2 (0.56) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL11171863 | 0.83 | DRD2 (0.64) | DRD2HTR2AHTR1AHTR7DRD4 | |
| SCHEMBL10836467 | 0.82 | DRD2 (0.55) | DRD2HTR2AHTR1AHTR7DRD4 | |
| SCHEMBL11172181 | 0.81 | DRD2 (0.61) | DRD2HTR2AHTR1AHTR7DRD4 | |
| SCHEMBL10836447 | 0.80 | DRD2 (0.73) | DRD2HTR2AHTR1AHTR7DRD4 | |
| SCHEMBL10414445 | 0.80 | DRD2 (0.73) | DRD2HTR2AHTR1AHTR7DRD4 | |
| SCHEMBL10414446 | 0.80 | DRD2 (0.73) | DRD2HTR2AHTR1AHTR7DRD4 | |
| SCHEMBL9401031 | 0.80 | HTR1A (0.95) | DRD2HTR2AHTR1AHTR7DRD4 | |
| Hydrochloric Acid SCHEMBL11263432 | 0.79 | DRD2 (0.64) | DRD2HTR2AHTR1A | |
| SCHEMBL11349330 | 0.78 | HTR1A (0.67) | DRD2HTR2AHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585773-A | DIURETIC, HYPOTENSIVE | BRISTOL-MYERS COMPANY (US) | 1986-04-29 | — | — | US | disclosed |