Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822296 | 0.73 | CYP17A1 (0.46) | HSP90AA1CYP19A1CASP3CYP26A1MAPT | |
| SCHEMBL4793589 | 0.68 | ALDH1A1 (0.47) | CASP3MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL4552738 | 0.66 | MEN1 (0.40) | CASP3ALDH1A1KMT2ATSHR | |
| SCHEMBL4624003 | 0.65 | TDP1 (0.49) | CASP3MAPTALDH1A1TDP1LMNA | |
| SCHEMBL461207 | 0.65 | CASP3 (0.44) | CASP3MAPTALDH1A1TDP1LMNA | |
| SCHEMBL4623781 | 0.65 | TDP1 (0.49) | CASP3MAPTALDH1A1TDP1LMNA | |
| SCHEMBL9064462 | 0.65 | TDP1 (0.49) | CASP3ALDH1A1TDP1LMNATP53 | |
| SCHEMBL11964484 | 0.65 | TDP1 (0.49) | CASP3MAPTALDH1A1TDP1LMNA | |
| SCHEMBL3259474 | 0.65 | CASP3 (0.44) | CASP3MAPTALDH1A1TDP1LMNA | |
| SCHEMBL15561472 | 0.65 | TDP1 (0.49) | CASP3MAPTALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4568685-A | THROMBOXANE SYNTHETASE ENZYME INHIBITORS, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-02-04 | — | — | US | disclosed |