Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.61 |
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MPI | P34949 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837493 | 0.85 | HTR1A (0.65) | HTR1AHTR2AHTR7DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10838441 | 0.85 | HTR1A (0.65) | HTR1AHTR2AHTR7DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10837752 | 0.83 | DRD2 (0.57) | HTR1AHTR2AHTR7DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10837864 | 0.83 | DRD2 (0.61) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10837652 | 0.83 | SMN1; SMN2 (0.54) | HTR1AHTR2AHTR7DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10838709 | 0.82 | HTR1A (0.69) | HTR1AHTR2AHTR7DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10836483 | 0.82 | HTR1A (0.68) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10837311 | 0.81 | HTR1A (0.60) | HTR1AHTR2AHTR7DRD3DRD4 | |
| SCHEMBL10837319 | 0.80 | DRD3 (0.74) | HTR1AHTR2AHTR7DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10837678 | 0.79 | HTR1A (0.58) | HTR1AHTR2AHTR7DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4619932-A | CENTRAL NERVOUS SYSTEM CONTROLLERS; ANTI-SCHIZOPHRENIA AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-28 | — | — | US | disclosed |
| US-4567187-A | CENTRAL NERVOUS SYSTEM | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| US-4460593-A | Carbostyril derivatives, and central nervous system controlling agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4455422-A | ANTIHISTAMINES, CNS CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-19 | — | — | US | disclosed |