Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27568084 | 0.87 | ELANE (0.53) | MAPTTDP1LMNAELANEL3MBTL1 | |
| SCHEMBL8438374 | 0.76 | ATM (0.77) | MAPTTDP1LMNAL3MBTL1ATM | |
| SCHEMBL10838120 | 0.76 | CNR2 (0.45) | MAPTTDP1LMNAGAAELANE | |
| SCHEMBL11183749 | 0.75 | ATM (0.74) | MAPTTDP1LMNAL3MBTL1ATM | |
| SCHEMBL16858233 | 0.73 | KMO (0.72) | MAPTTDP1LMNAL3MBTL1ATM | |
| SCHEMBL9786573 | 0.72 | L3MBTL1 (0.53) | TDP1ELANEL3MBTL1ATMPOLB | |
| SCHEMBL19947459 | 0.71 | TUBB4A (0.46) | MAPTGAABACE1POLBHTT | |
| SCHEMBL12551733 | 0.71 | ATM (0.68) | MAPTTDP1L3MBTL1ATMRECQL | |
| SCHEMBL12900880 | 0.71 | MAPT (0.69) | MAPTTDP1LMNAGAAL3MBTL1 | |
| SCHEMBL5314324 | 0.71 | ELANE (0.70) | MAPTTDP1LMNAGAAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4610982-A | Anti-inflammatory benzo- and thieno-1,2-thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor | PFIZER INC. (US) | 1986-09-09 | — | — | US | claimed |