SCHEMBL2860844

SCHEMBL2860844

c1ccc(Oc2ccc(-c3ccc(Oc4ccc(-c5ccc(Oc6ccccc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.75
TSHR P16473 1/20 0.75
GSTP1 P09211 1/20 0.62
NR1H2 P55055 1/20 0.62
BAX Q07812 1/20 0.62
MAOA P21397 1/20 0.62
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
SCN4A P35499 1/20 0.54
TLR8 Q9NR97 1/20 0.52
SOS1 Q07889 1/20 0.50
CA9 Q16790 1/20 0.50
PARP10 Q53GL7 1/20 0.50
NISCH Q9Y2I1 1/20 0.50
PLA2G2A P14555 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197414 1.00 LTA4H (0.75) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL6406035 1.00 LTA4H (0.75) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL21921128 0.97 LTA4H (0.71) LTA4HTSHRGSTP1NR1H2BAX
Biphenyl SCHEMBL10838288 0.97 LTA4H (0.71) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL9190364 0.97 LTA4H (0.71) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL403667 0.97 LTA4H (0.71) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL31588897 0.94 LTA4H (0.67) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL2856821 0.94 LTA4H (0.65) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL10686173 0.94 LTA4H (0.65) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL3681820 0.94 LTA4H (0.65) LTA4HTSHRGSTP1NR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754844-B2 Polyarylene ether compound containing sulfonic acid group, composition containing same, and method for manufacturing those TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-07-13 US disclosed
EP-1561768-B1 POLYARYLENE ETHER COMPOUND CONTAINING SULFONIC ACID GROUP, COMPOSITION CONTAINING SAME, AND METHOD FOR MANUFACTURING THOSE TOYO BOSEKI (JP) 2009-09-30 EP disclosed
US-20060166048-A1 Polyarylene ether compound containing sulfonic acid group, composition containing same, and method for manufacturing those TOYO BOSEKI KABUSHIKI KAISHA (JP) 2006-07-27 US disclosed
EP-1561768-A1 POLYARYLENE ETHER COMPOUND CONTAINING SULFONIC ACID GROUP, COMPOSITION CONTAINING SAME, AND METHOD FOR MANUFACTURING THOSE Toyo Boseki Kabushiki Kaisha (JP) 2005-08-10 EP disclosed
EP-0135938-B1 PROCESS FOR PRODUCING AROMATIC POLYETHER KETONES AND POLYTHIOETHER KETONES MITSUBISHI KASEI CORPORATION (JP) 1988-06-22 EP disclosed
US-4707536-A Catalytic preparation of aromatic polyketone from phosgene and aromatic ether or sulfide MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-11-17 US disclosed
US-4661581-A REACTING AROMATIC ETHERS OR THIOETHERS WITH PHOSGENE IN AN APROTIC SOLVENT WITH GROUP 3 METAL HALIDE CATALYST MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1987-04-28 US disclosed
EP-0135938-A2 Process for producing aromatic polyether ketones and polythioether ketones MITSUBISHI KASEI CORPORATION (JP) 1985-04-03 EP disclosed