Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 9/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840374 | 0.84 | NSD2 (0.42) | ALDH1A1HSD17B10TDP1DAOCYP3A4 | |
| SCHEMBL8024917 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1DAOCYP3A4 | |
| SCHEMBL10841338 | 0.72 | ALDH1A1 (0.63) | ALDH1A1HSD17B10TDP1CYP3A4KDM4E | |
| SCHEMBL10840500 | 0.71 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TDP1DAOCYP3A4 | |
| SCHEMBL10840555 | 0.67 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TDP1CYP3A4KDM4E | |
| SCHEMBL4193038 | 0.64 | CES1 (0.46) | ALDH1A1HSD17B10TDP1CYP3A4KDM4E | |
| SCHEMBL21196628 | 0.63 | DAO (0.57) | ALDH1A1DAOAGTR1MAPTPOLB | |
| SCHEMBL26649009 | 0.63 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TDP1CYP3A4KDM4E | |
| SCHEMBL2719064 | 0.63 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TDP1CYP3A4KDM4E | |
| SCHEMBL6657633 | 0.63 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |