Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 14/20 | 0.45 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940184 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP3A4TDP1KDM4E | |
| SCHEMBL8024917 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CYP3A4TDP1KDM4E | |
| SCHEMBL10840500 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CYP3A4TDP1KDM4E | |
| SCHEMBL26649009 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CYP3A4TDP1KDM4E | |
| SCHEMBL6657633 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CYP3A4TDP1KDM4E | |
| SCHEMBL27305823 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP3A4TDP1KDM4E | |
| SCHEMBL4704892 | 0.71 | PGR (0.59) | ALDH1A1HSD17B10CYP3A4TDP1KDM4E | |
| SCHEMBL4702454 | 0.71 | NR3C1 (0.70) | ALDH1A1HSD17B10CYP3A4TDP1NR3C1 | |
| SCHEMBL27478314 | 0.70 | PGR (0.58) | ALDH1A1HSD17B10CYP3A4TDP1KDM4E | |
| SCHEMBL24972224 | 0.69 | NR3C1 (0.54) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088785-B2 | Therapeutic compound and treatments | MEDISYN TECHNOLOGIES, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088785-B2 | Therapeutic compound and treatments | MEDISYN TECHNOLOGIES, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100137253-A1 | THERAPEUTIC COMPOUND AND TREATMENTS | MEDISYN TECHNOLOGIES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100137253-A1 | THERAPEUTIC COMPOUND AND TREATMENTS | MEDISYN TECHNOLOGIES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7652029-B2 | Therapeutic compound and treatments | MEDISYN TECHNOLOGIES, INC. (US) | 2010-01-26 | — | — | US | disclosed |
| US-7652029-B2 | Therapeutic compound and treatments | MEDISYN TECHNOLOGIES, INC. (US) | 2010-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137253-A1 | THERAPEUTIC COMPOUND AND TREATMENTS | MDH1, MDH2, MBOAT7 | ALDH1A1 2231/4885HSD17B10 1006/4885CYP3A4 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.