Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840500 | 0.84 | ALDH1A1 (0.53) | NSD2BCHEDAOCES1ALDH1A1 | |
| SCHEMBL10840158 | 0.78 | CES1 (0.42) | CES1ALDH1A1TDP1CYP3A4HSD17B10 | |
| SCHEMBL10841338 | 0.73 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4HSD17B10PGR | |
| SCHEMBL9529728 | 0.69 | CNR2 (0.42) | NSD2BCHEDAOCES1ALDH1A1 | |
| SCHEMBL10839816 | 0.67 | HTR2C (0.36) | NSD2BCHEDAOCES1TGM2 | |
| SCHEMBL10840161 | 0.65 | ALDH1A1 (0.44) | CES1ALDH1A1TDP1CYP3A4HSD17B10 | |
| SCHEMBL8024917 | 0.64 | ALDH1A1 (0.56) | DAOALDH1A1TDP1CYP3A4HSD17B10 | |
| SCHEMBL10840367 | 0.63 | KDM4E (0.47) | CES1ALDH1A1TDP1CYP3A4HSD17B10 | |
| SCHEMBL7477188 | 0.62 | NSD2 (0.53) | NSD2BCHEDAOCES1ALDH1A1 | |
| SCHEMBL5504578 | 0.62 | CES1 (0.46) | CES1ALDH1A1TDP1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |