Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877591 | 0.85 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6923261 | 0.82 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6923257 | 0.82 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3702527 | 0.81 | PDE4B (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6831510 | 0.78 | SLC6A2 (0.78) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6831507 | 0.78 | SLC6A2 (0.78) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5006473 | 0.77 | ALDH1A1 (0.45) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27674744 | 0.76 | SIGMAR1 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20942840 | 0.76 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18245295 | 0.76 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190496-A2 | Piperidine derivatives having a gastro-intestinal activity | BEECHAM GROUP PLC (GB) | 1986-08-13 | — | — | EP | disclosed |