Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841507 | 0.79 | HTR2C (0.37) | HTR2CDAOPDE7AHTR5ACA12 | |
| SCHEMBL10840825 | 0.78 | HTR2C (0.36) | HTR2CPDE7AHTR5ACA12CA1 | |
| SCHEMBL29789696 | 0.78 | HTR2C (0.36) | HTR2CPDE7AHTR5ACA12CA1 | |
| SCHEMBL4456748 | 0.78 | ADAMTS4 (0.30) | CA1CA2 | |
| SCHEMBL29789738 | 0.75 | HTR5A (0.36) | HTR2CHTR5ACA12CA1CA2 | |
| SCHEMBL10841248 | 0.75 | HTR5A (0.36) | HTR2CHTR5ACA12CA1CA2 | |
| SCHEMBL10838940 | 0.74 | CES1 (0.34) | CES1PDE7A | |
| SCHEMBL10838754 | 0.74 | AR (0.41) | CES1PDE7A | |
| SCHEMBL10840373 | 0.73 | PDE7A (0.38) | PDE7A | |
| SCHEMBL9501975 | 0.71 | TDP1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |