Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799227 | 0.87 | NOTUM (0.43) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4799232 | 0.87 | NOTUM (0.43) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14180297 | 0.85 | KDM2B (0.45) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4799260 | 0.85 | ALDH1A1 (0.39) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10839714 | 0.84 | HRH3 (0.40) | KDM4EKMT2AALDH1A1HPGDPOLB | |
| SCHEMBL4801000 | 0.81 | AGTR2 (0.42) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10839275 | 0.81 | HRH3 (0.38) | KDM4EKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10839670 | 0.81 | MEN1 (0.39) | MEN1KMT2AALDH1A1HTTHPGD | |
| SCHEMBL10839706 | 0.78 | ALDH1A1 (0.49) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10838330 | 0.74 | HPGD (0.35) | KDM4EHPGDMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584387-A | INTERMEDIATES FOR ALPHA-HYDROXY ALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0050351-B1 | OPTICALLY ACTIVE OR RACEMIC ALPHA-HYDROXYALDEHYDES AND BENZYL DERIVATIVES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-03-27 | — | — | EP | disclosed |
| US-4383122-A | HYDROCARBOYL-1,3-DIAZABICYCLO(3.3.0)OCTANE, GRIGNARD REAGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0011417-B1 | OPTICALLY ACTIVE OR RACEMIC AMINAL DERIVATIVES, PROCESS FOR PREPARING SAME AND FOR CONVERTING SAME TO ALPHA-HYDROXYALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-04 | — | — | EP | disclosed |
| US-4337346-A | CONDENSATION OF A GLYOXAL WITH AN N-SUBSTITUTED AMINOMETHYLPYRROLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0011417-A1 | Optically active or racemic aminal derivatives, process for preparing same and for converting same to alpha-hydroxyaldehydes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-28 | — | — | EP | disclosed |