Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 10/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840092 | 0.84 | PDE7A (0.40) | PDE7AARPGRAKT1 | |
| SCHEMBL10840084 | 0.84 | AKT1 (0.41) | ARSRD5A1CES1HTR2AHTR2C | |
| SCHEMBL10841141 | 0.75 | AHR (0.43) | PDE7AARADRA2ACES1HTR2A | |
| SCHEMBL10877453 | 0.75 | PTGS1 (0.39) | MEN1KMT2AHTR2AAKR1B1AKT1 | |
| SCHEMBL10840683 | 0.71 | HTR2A (0.37) | PDE7AARADRA2ASRD5A1CES1 | |
| SCHEMBL10841146 | 0.71 | AR (0.47) | ARADRA2ASRD5A1HTR2AHTR2C | |
| SCHEMBL10840689 | 0.70 | AR (0.49) | ARPGRNR3C2 | |
| SCHEMBL10841314 | 0.70 | CES1 (0.38) | PDE7AARSRD5A1CES1HTR2A | |
| SCHEMBL31243559 | 0.68 | HTR2A (0.46) | PDE7AARSRD5A1HTR2AHTR2C | |
| SCHEMBL4869956 | 0.67 | MEN1 (0.56) | MEN1KMT2AL3MBTL1CES1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |