Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | PNMT | P11086 | 6/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841314 | 0.84 | CES1 (0.38) | HTR2AHTR2CHTR2BCES1AR | |
| SCHEMBL10840116 | 0.84 | AR (0.32) | HTR2AHTR2CARPDE7ASRD5A1 | |
| SCHEMBL10841141 | 0.79 | AHR (0.43) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL10839029 | 0.73 | KDM4E (0.32) | AR | |
| SCHEMBL10840056 | 0.71 | PDE7A (0.36) | HTR2AHTR2CADRA2ACES1AR | |
| SCHEMBL10840092 | 0.70 | PDE7A (0.40) | ARPDE7A | |
| SCHEMBL10839480 | 0.69 | HTR5A (0.41) | ARPDE7A | |
| SCHEMBL10840441 | 0.68 | PDE7A (0.37) | ARPDE7A | |
| SCHEMBL31243559 | 0.68 | HTR2A (0.46) | HTR2AHTR2CHTR2BARPDE7A | |
| SCHEMBL29789651 | 0.68 | HTR5A (0.40) | ADRA2AARPDE7ASRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |