Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839480 | 0.80 | HTR5A (0.41) | HTR5APDE7ADAOAR | |
| SCHEMBL10840683 | 0.79 | HTR2A (0.37) | PDE7AADRA2AADRA2BADRA2CPNMT | |
| SCHEMBL10840955 | 0.79 | HTR5A (0.40) | HTR5APDE7AADRA2AAR | |
| SCHEMBL29789651 | 0.79 | HTR5A (0.40) | HTR5APDE7AADRA2AAR | |
| SCHEMBL10840441 | 0.79 | PDE7A (0.37) | PDE7AAR | |
| SCHEMBL10841314 | 0.77 | CES1 (0.38) | PDE7AHTR2CCES1ARHTR2A | |
| SCHEMBL29789658 | 0.76 | HTR5A (0.45) | HTR5AADRA2AHTR2C | |
| SCHEMBL6986075 | 0.76 | HTR5A (0.45) | HTR5AADRA2AHTR2C | |
| SCHEMBL10841360 | 0.76 | AR (0.33) | AR | |
| SCHEMBL10840056 | 0.75 | PDE7A (0.36) | PDE7AADRA2AHTR2CCES1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |