Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4834040 | 0.83 | HSPB1 (0.50) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL4203388 | 0.80 | TSHR (0.67) | ALDH1A1TSHRLMNAABCG2CHRNB2 | |
| SCHEMBL8968405 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNALTA4HMEN1 | |
| SCHEMBL4456862 | 0.79 | ALDH1A1 (0.60) | ALDH1A1TSHRLMNAABCG2CHRNB2 | |
| SCHEMBL30043252 | 0.78 | TSHR (0.64) | ALDH1A1TSHRLMNAABCG2CHRNB2 | |
| SCHEMBL6273333 | 0.78 | TSHR (0.64) | ALDH1A1TSHRLMNAABCG2CHRNB2 | |
| SCHEMBL11453175 | 0.77 | LMNA (0.57) | ALDH1A1TSHRLMNAABCG2CHRNB2 | |
| SCHEMBL9158141 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNACHRNB2CHRNA4 | |
| SCHEMBL9356592 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNACHRNB2CHRNA4 | |
| SCHEMBL10840704 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNAABCG2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578107-A | Herbicidal imidazolidine-2-one derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1986-03-25 | — | — | US | disclosed |