Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840861 | 0.85 | PGR (0.40) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL10840316 | 0.78 | PGR (0.42) | PGRAR | |
| SCHEMBL9306599 | 0.71 | PGR (0.38) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL29789712 | 0.71 | HTR2B (0.38) | ALDH1A1PGRAR | |
| SCHEMBL2175208 | 0.71 | PGR (0.38) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL29117338 | 0.71 | HTR2C (0.38) | PGRAR | |
| SCHEMBL10841242 | 0.68 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL29789697 | 0.68 | MAPT (0.50) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL23123274 | 0.67 | PGR (0.39) | KDM4EALDH1A1MAPTPGRAR | |
| SCHEMBL29789756 | 0.67 | PGR (0.39) | KDM4EALDH1A1MAPTPGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |