Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 12/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840490 | 0.84 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10840161 | 0.77 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10841338 | 0.77 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10840555 | 0.76 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10894057 | 0.73 | PGR (0.67) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL27524032 | 0.71 | PGR (0.75) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9529724 | 0.69 | LRRK2 (0.38) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL4180184 | 0.68 | PGR (0.74) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL4180527 | 0.67 | PGR (0.69) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9306599 | 0.67 | PGR (0.38) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |