Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 6/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839480 | 0.80 | HTR5A (0.41) | PDE7AARCA12CA1CA2 | |
| SCHEMBL10840955 | 0.79 | HTR5A (0.40) | PDE7AARCA12CA1CA2 | |
| SCHEMBL10841141 | 0.79 | AHR (0.43) | PDE7AAR | |
| SCHEMBL29789651 | 0.79 | HTR5A (0.40) | PDE7AARCA12CA1CA2 | |
| SCHEMBL6986075 | 0.76 | HTR5A (0.45) | — | |
| SCHEMBL29789658 | 0.76 | HTR5A (0.45) | — | |
| SCHEMBL10841360 | 0.76 | AR (0.33) | AR | |
| SCHEMBL10840425 | 0.75 | AR (0.45) | PDE7AAR | |
| SCHEMBL10840604 | 0.75 | KDM1A (0.34) | AR | |
| SCHEMBL756777 | 0.73 | LIG1 (0.41) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |