Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839480 | 0.76 | HTR5A (0.41) | ARTSHRALDH1A1 | |
| SCHEMBL23123951 | 0.75 | KDM1A (0.47) | KDM1AGAAPNMTARTSHR | |
| SCHEMBL29789927 | 0.75 | KDM1A (0.47) | KDM1AGAAPNMTARTSHR | |
| SCHEMBL10841141 | 0.75 | AHR (0.43) | PNMTARHTR2AHTR2CHTR2B | |
| SCHEMBL10840955 | 0.75 | HTR5A (0.40) | ARDRD2 | |
| SCHEMBL10840441 | 0.75 | PDE7A (0.37) | AR | |
| SCHEMBL29789651 | 0.75 | HTR5A (0.40) | ARDRD2 | |
| SCHEMBL29789658 | 0.72 | HTR5A (0.45) | DRD2HTR2C | |
| SCHEMBL10841360 | 0.72 | AR (0.33) | AR | |
| SCHEMBL6986075 | 0.72 | HTR5A (0.45) | DRD2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |