Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838799 | 0.84 | AR (0.34) | ARMTNR1A | |
| SCHEMBL19511212 | 0.75 | AR (0.35) | MEN1KMT2AARMTNR1AADRA2A | |
| SCHEMBL10840649 | 0.74 | AR (0.37) | ARMTNR1A | |
| SCHEMBL10840386 | 0.73 | AR (0.36) | KDM4EMEN1ALOX15KMT2AHSD17B10 | |
| SCHEMBL10841335 | 0.72 | AHR (0.37) | ARMTNR1AADRA2APNMTADRA2B | |
| SCHEMBL10840801 | 0.70 | AR (0.47) | ARMTNR1AADRA2APNMTADRA2B | |
| SCHEMBL19511225 | 0.69 | AR (0.36) | MEN1KMT2AARMTNR1A | |
| SCHEMBL9065009 | 0.69 | AR (0.49) | MEN1KMT2AARMTNR1APNMT | |
| SCHEMBL22262591 | 0.67 | MTNR1A (0.60) | ARMTNR1A | |
| SCHEMBL20870486 | 0.67 | MTNR1A (0.60) | ARMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |