Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838799 | 0.79 | AR (0.34) | MTNR1AHTR2CARMAPTHTR2B | |
| SCHEMBL10841078 | 0.78 | HTR2C (0.41) | AHRHTR2CHTR5AMAPTTAS1R3 | |
| SCHEMBL9065009 | 0.77 | AR (0.49) | MTNR1AHTR2CARHTR2BPNMT | |
| SCHEMBL29659962 | 0.73 | MTNR1A (0.60) | MTNR1AARMAPTHTR1A | |
| SCHEMBL22262591 | 0.73 | MTNR1A (0.60) | MTNR1AARMAPTHTR1A | |
| SCHEMBL20870486 | 0.73 | MTNR1A (0.60) | MTNR1AARMAPTHTR1A | |
| SCHEMBL4139663 | 0.73 | MTNR1A (0.60) | MTNR1AARMAPTHTR1A | |
| SCHEMBL29659944 | 0.73 | MTNR1A (0.60) | MTNR1AARMAPTHTR1A | |
| SCHEMBL10840792 | 0.72 | KDM4E (0.39) | MTNR1AARADRA2AADRA2BADRA2C | |
| SCHEMBL19511212 | 0.71 | AR (0.35) | MTNR1AARADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |