Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 7/20 | 0.49 |
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417149 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL13905780 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL6566824 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL14283945 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL3381317 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL16778351 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL30973127 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTPGRARNR3C1 | |
| Hydrochloric Acid SCHEMBL3378762 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL30973176 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL10840878 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HTTPGRARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |