Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 9/20 | 0.53 |
| ▸ | PGR | P06401 | 8/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13905780 | 1.00 | ALDH1A1 (0.63) | ALDH1A1HTTARPGRNR3C1 | |
| SCHEMBL6141613 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HTTARPGRNR3C1 | |
| SCHEMBL29837461 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HTTARPGRNR3C1 | |
| SCHEMBL3381317 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTARPGRNR3C1 | |
| SCHEMBL10840856 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTARPGRNR3C1 | |
| SCHEMBL16778351 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTARPGRNR3C1 | |
| SCHEMBL14283945 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTARPGRNR3C1 | |
| SCHEMBL30973127 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HTTARPGRNR3C1 | |
| SCHEMBL30973176 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTARPGRNR3C1 | |
| Hydrochloric Acid SCHEMBL3378762 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTARPGRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4692258-A | Tetrahydroquinolines as antioxidants for lubricants | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | claimed |
| EP-0072349-B1 | TETRAHYDROQUINOLINE AS AN ANTIOXIDANT FOR LUBRICANTS | CIBA-GEIGY AG (CH) | 1987-05-13 | — | — | EP | claimed |
| EP-0072349-A2 | Tetrahydroquinoline as an antioxidant for lubricants | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | claimed |
| EP-1406628-A1 | TETRAHYDROQUINOLINE DERIVATIVES | Akzo Nobel N.V. (NL) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003004028-A1 | TETRAHYDROQUINOLINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2003-01-16 | — | — | WO | disclosed |
| US-4692258-A | Tetrahydroquinolines as antioxidants for lubricants | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0072349-A2 | Tetrahydroquinoline as an antioxidant for lubricants | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |