Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 9/20 | 0.49 |
| ▸ | AR | P10275 | 7/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4165537 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL6566824 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL13905780 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL10840856 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL14283945 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL3381317 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL30973127 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL30973176 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HTTPGRARNR3C1 | |
| Hydrochloric Acid SCHEMBL3378762 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL26644708 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HTTPGRARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819336-A | Preparation method of 6-fluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline | 江苏百康德医药科技有限公司 | 2023-03-21 | — | — | CN | claimed |
| US-12570601-B2 | Process for preparing (R)-4-aminoindane and corresponding amides | FMC AGRO SINGAPORE PTE. LTD. (SG) | 2026-03-10 | — | — | US | disclosed |
| US-11851388-B2 | Compound of 1-acetyl-6-fluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline | FMC AGRO SINGAPORE PTE. LTD. (SG) | 2023-12-26 | — | — | US | disclosed |
| CN-115819336-A | Preparation method of 6-fluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline | 江苏百康德医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819336-A | Preparation method of 6-fluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline | 江苏百康德医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819336-A | Preparation method of 6-fluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline | 江苏百康德医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| US-11477983-B2 | Synergistic compositions for the protection of agrarian crops and the use thereof | STICHTING I-F PRODUCT COLLABORATION (NL) | 2022-10-25 | — | — | US | disclosed |
| US-20220315521-A1 | PROCESS FOR PREPARING (R)-4-AMINOINDANE AND CORRESPONDING AMIDES | FMC AGRICULTURAL PRODUCTS INTERNATIONAL AG (CH) | 2022-10-06 | — | — | US | disclosed |
| CN-109071439-B | Process for preparing 4-aminoindane derivatives and related aminoindane amides | I-F产品协作基金会 | 2022-07-15 | — | — | CN | disclosed |
| CN-114728884-A | Process for the preparation of (R) -4-aminoindanes and corresponding amides | FMC农产品国际有限公司 | 2022-07-08 | — | — | CN | disclosed |
| US-20200231533-A1 | PROCESSES FOR PREPARATION OF 4-AMINOINDANE COMPOUNDS AND RELATED AMINOINDANE AMIDES | FMC IP TECHNOLOGY GMBH (CH) | 2020-07-23 | — | — | US | disclosed |
| US-10640454-B2 | Processes for preparation of 4-aminoindane compounds and related aminoindane amides | STICHTING I-F PRODUCT COLLABORATION (NL) | 2020-05-05 | — | — | US | disclosed |
| EP-3442944-B1 | PROCESS FOR THE PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES | STICHTING I F PRODUCT COLLABORATION (NL) | 2020-04-15 | — | — | EP | disclosed |
| US-20190119195-A1 | PROCESSES FOR PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES | FMC IP TECHNOLOGY GMBH (CH) | 2019-04-25 | — | — | US | disclosed |
| US-10143200-B2 | Synergistic compositions for the protection of agrarian crops and the use thereof | STICHTING I-F PRODUCT COLLABORATION (NL) | 2018-12-04 | — | — | US | disclosed |
| CN-104602523-B | Synergistic composition of protection cultivation crop and application thereof | I-F产品协作基金会 | 2017-12-15 | — | — | CN | disclosed |
| WO-2017178868-A1 | PROCESS FOR THE PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES | STICHTING I-F PRODUCT COLLABORATION (NL) | 2017-10-19 | — | — | WO | disclosed |
| US-20150164076-A1 | SYNERGISTIC COMPOSITIONS FOR THE PROTECTION OF AGRARIAN CROPS AND THE USE THEREOF | FMC IP TECHNOLOGY GMBH (CH) | 2015-06-18 | — | — | US | disclosed |
| US-20150164076-A1 | SYNERGISTIC COMPOSITIONS FOR THE PROTECTION OF AGRARIAN CROPS AND THE USE THEREOF | FMC IP TECHNOLOGY GMBH (CH) | 2015-06-18 | — | — | US | disclosed |
| US-20150164076-A1 | SYNERGISTIC COMPOSITIONS FOR THE PROTECTION OF AGRARIAN CROPS AND THE USE THEREOF | FMC IP TECHNOLOGY GMBH (CH) | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851388-B2 | Compound of 1-acetyl-6-fluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline | HDAC3, HDAC6, KAT2A | ALDH1A1 114/4885HTT 1713/4885PGR 3837/4885 |
| US-20150164076-A1 | SYNERGISTIC COMPOSITIONS FOR THE PROTECTION OF AGRARIAN CROPS AND THE USE THEREOF | CASP7, AADAC, CRY1 | ALDH1A1 2081/4885HTT 3356/4885PGR 4654/4885 |
| US-10640454-B2 | Processes for preparation of 4-aminoindane compounds and related aminoindane amides | AADAT, ALDH7A1, AAAS | ALDH1A1 246/4885HTT 1811/4885PGR 4763/4885 |
| US-20190119195-A1 | PROCESSES FOR PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES | ALDH7A1, AADAT, AASDHPPT | ALDH1A1 229/4885HTT 2024/4885PGR 4765/4885 |
| US-12570601-B2 | Process for preparing (R)-4-aminoindane and corresponding amides | CYP1B1, CHRM1, CYP11B2 | ALDH1A1 667/4885HTT 4663/4885PGR 2285/4885 |
| US-10143200-B2 | Synergistic compositions for the protection of agrarian crops and the use thereof | CASP7, AADAC, CRY1 | ALDH1A1 2081/4885HTT 3356/4885PGR 4654/4885 |
| US-11477983-B2 | Synergistic compositions for the protection of agrarian crops and the use thereof | CASP7, AADAC, CRY1 | ALDH1A1 2081/4885HTT 3356/4885PGR 4654/4885 |
| US-20200231533-A1 | PROCESSES FOR PREPARATION OF 4-AMINOINDANE COMPOUNDS AND RELATED AMINOINDANE AMIDES | AADAT, ALDH7A1, AAAS | ALDH1A1 328/4885HTT 1964/4885PGR 4807/4885 |
| US-20220315521-A1 | PROCESS FOR PREPARING (R)-4-AMINOINDANE AND CORRESPONDING AMIDES | AAAS, ADRA1D, NAT1 | ALDH1A1 682/4885HTT 3631/4885PGR 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.