Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10842419 | 0.87 | KDM4E (0.36) | CHEK1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL10843630 | 0.84 | ALDH1A1 (0.42) | CHEK1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL10842100 | 0.82 | NPC1 (0.37) | ALDH1A1MAPTHPGDLMNAMEN1 | |
| SCHEMBL10843797 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL10842466 | 0.80 | MEN1 (0.47) | CHEK1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL10840481 | 0.78 | KDM4E (0.52) | CHEK1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL10842071 | 0.75 | CHEK1 (0.37) | CHEK1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL10842421 | 0.65 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDKMT2AKDM4E | |
| SCHEMBL17477674 | 0.65 | MAPT (0.54) | ALDH1A1MAPTHPGDLMNAMEN1 | |
| SCHEMBL6125624 | 0.64 | EGLN2 (0.52) | ALDH1A1MAPTHPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |