Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840956 | 0.82 | NPSR1 (0.49) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10841340 | 0.81 | MAPT (0.43) | CHEK1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10842915 | 0.75 | CHEK1 (0.45) | CHEK1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10842466 | 0.71 | MEN1 (0.47) | CHEK1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL22307388 | 0.70 | ALDH1A1 (0.58) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10842419 | 0.63 | KDM4E (0.36) | CHEK1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10842100 | 0.60 | NPC1 (0.37) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10840481 | 0.59 | KDM4E (0.52) | CHEK1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13579637 | 0.58 | KDR (0.49) | CHEK1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10843797 | 0.58 | ALDH1A1 (0.40) | MAPTKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | claimed |
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |