Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629498 | 0.86 | BACE1 (0.50) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL6629500 | 0.86 | BACE1 (0.50) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL27563285 | 0.83 | MEN1 (0.48) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL27551193 | 0.82 | ALDH1A1 (0.59) | MEN1KMT2ARAB9ANPC1BACE1 | |
| SCHEMBL30832846 | 0.82 | MEN1 (0.57) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL1663438 | 0.82 | MEN1 (0.57) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL26604899 | 0.81 | MEN1 (0.51) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL5733017 | 0.81 | PKM (0.53) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL30024173 | 0.81 | PKM (0.53) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL1734030 | 0.81 | BACE1 (0.55) | MEN1KMT2ARAB9ANPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590280-A | Preparing indoline derivatives | THE UPJOHN COMPANY (US) | 1986-05-20 | — | — | US | disclosed |